About

NART: 99308-09924-00

This Dermatological Soothing Cream repairs the skin barrier during drying acne medications and provides:

  1. 48H LONG LASTING HYDRATION
  2. RESTORES SKIN BARRIER

It is fragrance-free and contains a unique combination of soothing Symsitive(TM) and repairing Ceramides. 

NON-COMEDOGENIC
FRAGRANCE FREE
SUITABLE ON VERY SENSITIVE SKIN
TESTED FOR ACNE-PRONE SKIN
SUITABLE ON ALL PHOTOTYPES
FSC-CERTIFIED PAPER

Main findings

-87%
REDNESS 1
-43%
SENSATION OF SKIN TIGHTNESS 2
100%
SAW IT SOOTHES THE SKIN 3

SLIDE TO DISCOVER THE EFFICACY

BeforeAfter

Clinical Formula

SymSitive®

SymSitive®, a neurosensory active ingredient, modulates TRPV1 (transient receptor potential vanilloid 1) which is a key thermoreceptor and pain mediator. This helps to counteract hypersensitivity reactions in the skin. Key benefits are: 

  • Instant & Long-Lasting Relief: Acts directly at the source of skin sensitivity, quickly reducing stinging, burning, and itching sensations caused by environmental and internal stressors.
  • Neurocalming Effect: Regulates overreactive sensory neurons, preventing hyperresponsiveness to triggers such as heat, mechanical stress, or chemical irritants.

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Ceramide 3

Ceramides are essential skin lipids that form a key component of the epidermal barrier.

They provide two main benefits:

  • Barrier Function: Ceramides strengthen and restore the skin’s protective barrier, preventing transepidermal water loss and shielding against environmental stressors.
  • Dry Skin Relief: By maintaining optimal hydration levels, ceramides alleviate symptoms of dryness, keeping the skin soft and resilient.
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How to Use

•  Apply the product every night on dry skin after cleansing with DERMOPURE Purifying Cleanser.
•  Avoid eye contact.

BUILD YOUR OWN ACNE PRONE SKIN PROTOCOL

Step 1: CLEANSE
DERMOPURE CLINICAL Purifying Cleanser
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Step 2: TREAT
DERMOPURE CLINICAL Hydra Repair
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Step 3: PROTECT
Eucerin Oil Control
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1 Clinical study, 59 subjects, image analysis, 2 weeks of use twice daily, percentage improvement to baseline

2 Clinical study, 59 subjects, image analysis, 2 weeks of use twice daily, percentage improvement to baseline

3 2 Product-in-use, 120 subjects, after 8 weeks

4.5
from 55 Reviews
Write a review
    17/09/2025
    Soothing cream for sensitive skin
    [This review was collected as part of a promotion.] I like that the cream is fragrance-free and doesn’t cause any stinging or side effects when I use it with tretinoin or adapalene. However, I have to rub it in properly so it sinks into the skin. It’s not oily, but it does sometimes pill, even if I only use a tiny amount. It keeps my skin moisturized until the next day, so I think it’s effective at keeping the skin hydrated. This cream would come in handy during winter.
    Chloejas9
    17/09/2025
    I wouldn't recommend
    [This review was collected as part of a promotion.] Using this was not a nice experience for me at all. Everytime I applied this it would end up peeling off my face and even when I would change up my routine it would still peel. I don’t know how it went for other people but if I can't even put it into my current routine I don't see a point in using it ever again.
    vroomvroom9
    17/09/2025
    Cream
    [This review was collected as part of a promotion.] I absolutely love this product. As someone who completed 6 months of roaccutane a few months ago this has been a game changer for my skin. It leaves it super soft and moisturised and doesn’t cause any breakouts.
    Hannah9
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*The authenticity of the reviews is not verified
dermopure clinical

DERMOPURE CLINICAL HYDRA REPAIR

    • 4.5
    55 reviews
Skin concerns
Acne prone skinUltra Sensitive Skin
This Dermatological Soothing Cream is recommended by dermatologists and clinically proven to repair the skin barrier while using drying acne medications. With Symsitive™ and ceramides to instantly reduce stinging, burning and itching.
Key Ingredients

SymSitive®, Ceramide 3

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Size
40 ml